Phosphorus pentachloride → 4-(Methylsulfonyl)benzenemethanesulfonyl chloride

HRID 1159468Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1159468
[CH3:1][S:2]([C:5]1[CH:10]=[CH:9][C:8]([CH2:11][S:12]([OH:15])(=O)=[O:13])=[CH:7][CH:6]=1)(=[O:4])=[O:3].[Na].P(Cl)(Cl)(Cl)(Cl)[Cl:18]>C(Cl)(Cl)Cl>[CH3:1][S:2]([C:5]1[CH:10]=[CH:9][C:8]([CH2:11][S:12]([Cl:18])(=[O:15])=[O:13])=[CH:7][CH:6]=1)(=[O:4])=[O:3]

Komponenten

5

Edukt 3

HCID 24819Phosphorus pentachlorideHCID 5360545SodiumHCID 17973788(4-Methanesulfonyl-phenyl)-methanesulfonic acid

Produkt 1

HCID 219624184-(Methylsulfonyl)benzenemethanesulfonyl chloride

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6212ChloroformLösungsmittel

Versuchsvorschrift

To the title A compound, (4-methanesulfonyl-phenyl)-methanesulfonic acid, sodium salt is added PCl5 (10 g) in 200 mL of chloroform and the mixture is stirred for 48 h. The solids are filtered off, the chloroform is removed by evaporation, and the residue is triturated with hexanes, and the solids are collected by filtration to afford (4-methanesulfonyl-phenyl)-methanesulfonyl chloride.

Aufarbeitung

  1. filtrationThe solids are filtered off
  2. customthe chloroform is removed by evaporation
  3. customthe residue is triturated with hexanes
  4. filtrationthe solids are collected by filtration

Quellen und Nachweise

ORD-Eintrag
ord-825b500b5e5f4abaaab796bd4af3530e
Quelldatensatz
uspto-grants-2010_10
Patentnummer
US07812167B2

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