Epichlorohydrin → HCID 19863794, Verbindung

HRID 1164932Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1164932
[OH:1][CH:2]([C:8]1[CH:9]=[C:10]([OH:14])[CH:11]=[CH:12][CH:13]=1)[CH2:3][CH2:4][CH2:5][CH2:6][CH3:7].[CH2:15]([CH:17]1[O:19][CH2:18]1)Cl.[OH-].[K+]>C(O)C.O>[OH:1][CH:2]([C:8]1[CH:9]=[C:10]([CH:11]=[CH:12][CH:13]=1)[O:14][CH2:15][CH:17]1[CH2:18][O:19]1)[CH2:3][CH2:4][CH2:5][CH2:6][CH3:7]

Komponenten

6

Edukt 3

HCID 7835EpichlorohydrinHCID 14797Potassium HydroxideHCID 117900843-(1-Hydroxyhexyl)phenol

Produkt 1

HCID 19863794HCID 19863794, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 702EthanolLösungsmittel2×HCID 962WaterLösungsmittel

Versuchsvorschrift

19.4 g. (0.1 mole) 3-(1-hydroxyhexyl)-phenol and 28.6 g. epichlorohydrin are dissolved in 25 ml. ethanol and heated to the boil. A solution of 6.6 g. potassium hydroxide in 3 ml. water and 25 ml. ethanol is then added dropwise thereto in the course of 15 minutes. The reaction mixture is boiled under reflux for 2 hours, the solvent is then distilled off and the residue is taken up in water. Extraction is carried out with ethyl acetate, the ethyl acetate phase is washed twice with aqueous sodium hydroxide solution and water, dried and evaporated to give 22.4 g. (89% of theory) of the title compound in the form of an oil.

Aufarbeitung

  1. customin the course of 15 minutes
  2. temperatureunder reflux for 2 hours
  3. distillationthe solvent is then distilled off
  4. extractionExtraction
  5. washthe ethyl acetate phase is washed twice with aqueous sodium hydroxide solution and water
  6. customdried
  7. customevaporated
  8. customto give 22.4 g

Quellen und Nachweise

ORD-Eintrag
ord-c8c56db0a61c438c80c6863e81f2eb53
Quelldatensatz
uspto-grants-1990_03
Patentnummer
US04906666

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