HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
17beta-(Hydroxymethyl)androst-4-ene-3-ol → 17beta-Hydroxymethyl-4-androsten-3-on
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 17beta-(Hydroxymethyl)androst-4-ene-3-ol | HCID 14801334 | — |
| Katalysator | HCID 178418406 | HCID 178418406 | — |
| Lösungsmittel | Chloroform | HCID 6212 | — |
| Produkt | 17beta-Hydroxymethyl-4-androsten-3-on | HCID 14377617 | 96,6% |
Reaktionsschritte
A solution of 17β-(hydroxymethyl)androst-4-ene-3-ol (27 g, 0.089 mol) in 1200 ml trichloromethane was treated with activated manganese dioxide (66 g). After 3 hours the mixture was filtered. Concentration afforded 26 g (96%) of 3-oxo-17β-(hydroxymethyl)-4-androstene (m.p. 151° C.).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04910226 |
| Quelldatensatz | uspto-grants-1990_03 |
| ORD ID | ord-45273ee02c8c41da99b027340de65951 |
| Quellennotiz | uspto-grants-1990_03 |