Water → 1-(2-Chloro-5-nitrophenyl)-2-(2,2-dimethylpropionyl)hydrazine

HRID 1165928

Reaktionsgleichung

Reaktionsgleichung von HRID 1165928
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([N+:8]([O-:10])=[O:9])=[CH:4][C:3]=1[NH:11][NH2:12].C(N(CC)CC)C.[C:20](Cl)(=[O:25])[C:21]([CH3:24])([CH3:23])[CH3:22].O>ClCCl>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([N+:8]([O-:10])=[O:9])=[CH:4][C:3]=1[NH:11][NH:12][C:20](=[O:25])[C:21]([CH3:24])([CH3:23])[CH3:22]

Komponenten

6

Edukt 4

HCID 962WaterHCID 8471TriethylamineHCID 62493Pivaloyl chlorideHCID 4103137(2-Chloro-5-nitrophenyl)hydrazine

Produkt 1

HCID 142806541-(2-Chloro-5-nitrophenyl)-2-(2,2-dimethylpropionyl)hydrazineAusbeute 77,5 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

To a solution of 2-chloro-5-nitrophenylhydrazine (37.60 g) in dichloromethane (200 ml), triethylamine (22.27 g) and pivaloyl chloride (26.59 g) were added, and the resultant mixture was stirred at room temperature for 12 hours. The reaction mixture was combined with water. The dichloromethane layer was washed with water, dried and concentrated under reduced pressure to give 1-(2-chloro-5-nitrophenyl)-2-(2,2-dimethylpropionyl)hydrazine (42.23 g). m.p., 153.3° C..

Aufarbeitung

  1. washThe dichloromethane layer was washed with water
  2. customdried
  3. concentrationconcentrated under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-8b0224c2604e45d4a79598f762f80c84
Quelldatensatz
uspto-grants-1990_03
Patentnummer
US04912225

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