Methanol → 3-(((S)-1-((1S,2R,4R)-4-(isopropyl(methyl)amino)-2-propylcyclohexyl)-2-oxopyrrolidin-3-yl)carbamoyl)-5-tert-butylbenzoic acid

Reaktionsgleichung

[NH2:1][C@H:2]1[CH2:6][CH2:5][N:4]([C@H:7]2[CH2:12][CH2:11][C@@H:10]([N:13]([CH:15]([CH3:17])[CH3:16])[CH3:14])[CH2:9][C@H:8]2[CH2:18][CH2:19][CH3:20])[C:3]1=[O:21].[C:22]([C:26]1[CH:27]=[C:28]([CH:32]=[C:33]([C:35](OC)=[O:36])[CH:34]=1)[C:29]([OH:31])=[O:30])([CH3:25])([CH3:24])[CH3:23].[Li+].[OH-].CO>CN(C=O)C.C(O)(C(F)(F)F)=O.O>[CH:15]([N:13]([CH3:14])[C@@H:10]1[CH2:11][CH2:12][C@H:7]([N:4]2[CH2:5][CH2:6][C@H:2]([NH:1][C:35]([C:33]3[CH:32]=[C:28]([CH:27]=[C:26]([C:22]([CH3:25])([CH3:24])[CH3:23])[CH:34]=3)[C:29]([OH:31])=[O:30])=[O:36])[C:3]2=[O:21])[C@H:8]([CH2:18][CH2:19][CH3:20])[CH2:9]1)([CH3:16])[CH3:17]