Bromine → 2-Bromo-1-[4-(4-chlorophenoxy)-2-propylphenyl]ethanone

Beteiligte Stoffe

Reaktionsschritte

To a solution of the product from Step 7 (1.2 g, 4.2 mmol) in dioxane (20 mL) at room temperature was added dropwise bromine (0.25 mL, 5.0 mmol). After 2 h at room temperature, the reaction mixture was diluted with ethyl acetate, washed with an aqueous solution of sodium thiosulfate and dried over magnesium sulfate. Removal of the solvent gave a residue which was purified by chromatography on silica gel to give the title product.

Herkunft & Nachweise