Tetrahydrofuran → 4-(3-tert-Butyl-5-{3-[2-fluoro-4-(2-methyl-pyridin-4-yloxy)phenyl]ureido}pyrazol-1-yl)-2-methyl-N-(2-morpholin-4-yl-ethyl)benzene-sulfonamide

Reaktionsgleichung

[NH2:1][C:2]1[N:6]([C:7]2[CH:12]=[CH:11][C:10]([S:13]([NH:16][CH2:17][CH2:18][N:19]3[CH2:24][CH2:23][O:22][CH2:21][CH2:20]3)(=[O:15])=[O:14])=[C:9]([CH3:25])[CH:8]=2)[N:5]=[C:4]([C:26]([CH3:29])([CH3:28])[CH3:27])[CH:3]=1.[F:30][C:31]1[CH:36]=[C:35]([O:37][C:38]2[CH:43]=[CH:42][N:41]=[C:40]([CH3:44])[CH:39]=2)[CH:34]=[CH:33][C:32]=1[NH2:45].C1C[O:49][CH2:48]C1>ClCCCl>[C:26]([C:4]1[CH:3]=[C:2]([NH:1][C:48]([NH:45][C:32]2[CH:33]=[CH:34][C:35]([O:37][C:38]3[CH:43]=[CH:42][N:41]=[C:40]([CH3:44])[CH:39]=3)=[CH:36][C:31]=2[F:30])=[O:49])[N:6]([C:7]2[CH:12]=[CH:11][C:10]([S:13]([NH:16][CH2:17][CH2:18][N:19]3[CH2:20][CH2:21][O:22][CH2:23][CH2:24]3)(=[O:15])=[O:14])=[C:9]([CH3:25])[CH:8]=2)[N:5]=1)([CH3:29])([CH3:28])[CH3:27]