HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-(5-Trifluoromethyl-pyridin-2-yloxy)-phenol → 3,4-dihydro-1H-isoquinoline-2-carboxylic acid 4-(5-trifluoromethylpyridin-2-yloxy)-phenyl ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-(5-Trifluoromethyl-pyridin-2-yloxy)-phenol | HCID 155241 | — |
| Edukt | 3-methyl-1-(1,2,3,4-tetrahydroisoquinoline-2-carbonyl)-1H-imidazol-3-ium iodide | HCID 22047918 | — |
| Produkt | 3,4-dihydro-1H-isoquinoline-2-carboxylic acid 4-(5-trifluoromethylpyridin-2-yloxy)-phenyl ester | HCID 23635514 | — |
Reaktionsschritte
The title compound was prepared from 4-(5-trifluoromethyl-pyridin-2-yloxy)-phenol and 3-(3,4-dihydro-1H-isoquinoline-2-carbonyl)-1-methyl-3H-imidazol-1-ium iodide. The crude product was recrystallized (ethanol) (53%). HPLC-MS m/z=415.2 (M+1), Rt: 5.3 min.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07279470B2 |
| Quelldatensatz | uspto-grants-2007_10 |
| ORD ID | ord-478889d52f73403380892516082929a6 |
| Quellennotiz | uspto-grants-2007_10 |