HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Trifluoroacetic acid → Trifluoroacetic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Trifluoroacetic acid | HCID 6422 | — |
| Edukt | {2-[4-(Methyl-phenyl-carbamoyloxy)-phenyl]-ethyl}-carbamic acid tertbutyl ester | HCID 69518850 | — |
| Lösungsmittel | Dichloromethane | HCID 6344 | — |
| Produkt | Trifluoroacetic acid | HCID 6422 | — |
| Produkt | Methyl-phenyl-carbamic acid 4-(2-amino-ethyl)phenyl Ester | HCID 69520583 | — |
Reaktionsschritte
{2-[4-(Methyl-phenyl-carbamoyloxy)-phenyl]-ethyl}-carbamic acid tertbutyl ester(3.7 g; 10 mmol) from above was dissolved in CH2Cl2 (90 mL). Addition of TFA (6 mL) and stirring for 4 h. The reaction mixture was evaporated to dryness and dried in vacuo at 50° C. overnight producing the title compound as a TFA salt in quantitative yield as yellow hygroscopic crystals.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07279470B2 |
| Quelldatensatz | uspto-grants-2007_10 |
| ORD ID | ord-72fdee7c52474c0a818034ace34960c5 |
| Quellennotiz | uspto-grants-2007_10 |