HCID 68600578, Verbindung → HCID 68599400, Verbindung
Reaktionsgleichung
[F:1][C:2]([F:29])([F:28])[CH2:3][CH2:4][O:5][C:6]([N:8]1[CH2:13][CH2:12][N:11]([C:14](=[O:27])[CH2:15][NH:16]C(OCC2C=CC=CC=2)=O)[CH2:10][CH2:9]1)=[O:7]>C(O)C.[Pd]>[F:29][C:2]([F:1])([F:28])[CH2:3][CH2:4][O:5][C:6]([N:8]1[CH2:13][CH2:12][N:11]([C:14](=[O:27])[CH2:15][NH2:16])[CH2:10][CH2:9]1)=[O:7]Komponenten
4
Reagenzien, Katalysatoren, Lösungsmittel 2
Versuchsvorschrift
To a solution of 1.63 g 4-(2-Benzyloxycarbonylamino-acetyl)-piperazine-1-carboxylic acid 3,3,3-trifluoro-propyl ester in 40 ml ethanol were added 200 mg Pd/C (10%) and the suspension stirred under an atmosphere of hydrogen (3 bar) for 12 h. The reaction mixture was filtrated over a plug of Celite®, washed with ethanol and concentrated. Yield: 1.02 g colorless oil.