Hydrazine hydrate (1:1) → 4-Phenoxybutan-1-amine

HRID 1198119Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1198119
[O:1]([CH2:8][CH2:9][CH2:10][CH2:11][N:12]1C(=O)C2=CC=CC=C2C1=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.O.NN>C(O)C>[O:1]([CH2:8][CH2:9][CH2:10][CH2:11][NH2:12])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Komponenten

4

Edukt 2

HCID 24654Hydrazine hydrate (1:1)HCID 166375972-(4-Phenoxybutyl)-1H-isoindole-1,3(2H)-dione

Produkt 1

HCID 1162404-Phenoxybutan-1-amineAusbeute 96,2 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

A mixture of N-(4-phenoxybutyl)phthalimide (7.8 g), hydrazine hydrate (7 ml) and ethanol (150 ml) was stirred for one hour under reflux. Crystalline precipitate was filtered off, then the filtrate was concentrated under reduced pressure to give 4-phenoxybutylamine (4.2 g, 95%) as an oily product.

Aufarbeitung

  1. temperatureunder reflux
  2. filtrationCrystalline precipitate was filtered off
  3. concentrationthe filtrate was concentrated under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-43de905befef4fd6a66a6a7f25f015a2
Quelldatensatz
uspto-grants-1994_01
Patentnummer
US05280022

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