(E)-3-(1H-Indol-7-yl)acrylonitrile → 3-(1H-Indol-7-YL)propanenitrile

HRID 1198536

Reaktionsgleichung

Reaktionsgleichung von HRID 1198536
[C:1](/[CH:3]=[CH:4]/[C:5]1[CH:6]=[CH:7][CH:8]=[C:9]2[C:13]=1[NH:12][CH:11]=[CH:10]2)#[N:2]>C(O)C.[Pd]>[C:1]([CH2:3][CH2:4][C:5]1[CH:6]=[CH:7][CH:8]=[C:9]2[C:13]=1[NH:12][CH:11]=[CH:10]2)#[N:2]

Komponenten

4

Edukt 1

HCID 19959103(E)-3-(1H-Indol-7-yl)acrylonitrile

Produkt 1

HCID 199591053-(1H-Indol-7-YL)propanenitrile

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 702EthanolLösungsmittel

Versuchsvorschrift

A solution of 7-[2-(E)-cyanoethenyl]indole (0.28 g) in ethanol (75 ml) was hydrogenated at 50 psi over 10% palladium on charcoal (0.1 g) for 4 hours. The catalyst was filtered off and the filtrate was evaporated to give the product.

Aufarbeitung

  1. filtrationThe catalyst was filtered off
  2. customthe filtrate was evaporated
  3. customto give the product

Quellen und Nachweise

ORD-Eintrag
ord-0f8edb9087e34736b4582c2d32ffe841
Quelldatensatz
uspto-grants-1994_01
Patentnummer
US05281593

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