Ethanol → [(1,3,4-Thiadiazol-2,5-diyl)dithio]-bis(2,2'-succinic acid)

HRID 1199826

Reaktionsgleichung

Reaktionsgleichung von HRID 1199826
[OH-:1].[K+].[CH2:3]([OH:5])[CH3:4].[SH:6][C:7]1[S:8][C:9]([SH:12])=[N:10][N:11]=1.Br[CH:14]([CH2:18][C:19]([OH:21])=[O:20])[C:15]([OH:17])=[O:16]>O>[S:8]1[C:9]([S:12][CH:4]([CH2:14][C:15]([OH:17])=[O:16])[C:3]([OH:1])=[O:5])=[N:10][N:11]=[C:7]1[S:6][CH:14]([CH2:18][C:19]([OH:21])=[O:20])[C:15]([OH:17])=[O:16]

Komponenten

6

Edukt 4

HCID 702Ethanol4×HCID 14797Potassium Hydroxide2×HCID 73557Bromosuccinic acidHCID 178418558HCID 178418558, Verbindung

Produkt 1

HCID 14646898[(1,3,4-Thiadiazol-2,5-diyl)dithio]-bis(2,2'-succinic acid)

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

About 68 g. of a solution of 39.6 g. (0.6 mole) of KOH (85%) in 200 ml. of abs. ethanol is added to a stirred slurry of 15.0 g. (0.1 mole) of 2,5-dimercapto-1,3,4-thiadiazole in 80 ml. of abs. ethanol, at 10°-15° C. The resultant mixture is stirred at 10°-15° C. for a half hour, and thereafter, a clear solution of 39.4 g. (0.2 mole) of bromosuccinic acid in 70 ml. of abs. ethanol is added dropwise over a period of 15 minutes at 10°-15° C. followed by the gradual addition of the remainder of the KOH solution at the same temperature range over a period of 15 minutes. After adding 100 ml. of abs. ethanol, the reaction mixture is stirred in the cooling bath for more than one hour, then overnight in water bath at ambient temperature.

Aufarbeitung

  1. customat 10°-15° C
  2. additionAfter adding 100 ml
  3. customat ambient temperature

Quellen und Nachweise

ORD-Eintrag
ord-c11e7d0b57d8404191c7aeaff24d0bf2
Quelldatensatz
uspto-grants-1990_02
Patentnummer
US04902804

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