2-(3-Methoxy-prop-1-ynyl)-phenoxy-acetic acid ethyl ester → HCID 67072081, Verbindung

HRID 1242278Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1242278
[CH2:1]([O:3][C:4](=[O:18])[CH2:5][O:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[C:13]#[C:14][CH2:15][O:16][CH3:17])[CH3:2]>CCOC(C)=O.[Pd]>[CH2:1]([O:3][C:4](=[O:18])[CH2:5][O:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[CH2:13][CH2:14][CH2:15][O:16][CH3:17])[CH3:2]

Komponenten

4

Edukt 1

HCID 670722722-(3-Methoxy-prop-1-ynyl)-phenoxy-acetic acid ethyl ester

Produkt 1

HCID 67072081HCID 67072081, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 8857Ethyl AcetateLösungsmittel

Versuchsvorschrift

9.54 g (38.4 mmol) of the above prepared [2-(3-methoxy-prop-1-ynyl)-phenoxy]-acetic acid ethyl ester was hydrogenated at RT in 130 ml of AcOEt over 2.39 g of Pd/C (10%) under 1 atm of H2-pressure. After 2 h at ambient temperature, the reaction mixture was filtrated over Celite and carefully rinsed with AcOEt. Evaporation of the solvent left finally 9.39 g of the title compound as colorless oil.

Aufarbeitung

  1. filtrationthe reaction mixture was filtrated over Celite
  2. washcarefully rinsed with AcOEt
  3. customEvaporation of the solvent
  4. waitleft finally 9.39 g of the title compound as colorless oil

Quellen und Nachweise

ORD-Eintrag
ord-357df83964494af6a97e52c9a03907cc
Quelldatensatz
uspto-grants-2006_10
Patentnummer
US07115611B2

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