Methyl Isocyanate → HCID 20279741, Verbindung

HRID 1247869Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1247869
Cl.[CH2:2]([NH:14][NH2:15])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH3:13].[OH-].[K+].[CH3:18][N:19]=[C:20]=[O:21]>C(OCC)C>[CH3:18][NH:19][C:20]([N:14]([CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH3:13])[NH2:15])=[O:21]

Komponenten

5

Edukt 3

HCID 12228Methyl IsocyanateHCID 14797Potassium HydroxideHCID 20279742HCID 20279742, Verbindung

Produkt 1

HCID 20279741HCID 20279741, VerbindungAusbeute 94,7 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 3283Diethyl EtherLösungsmittel2×

Versuchsvorschrift

A stirred, degassed suspension of dodecylhydrazine hydrochloride (4.62 g, 0.017 mole) in diethyl ether (15 mL) was cooled under nitrogen and 4N aqueous potassium hydroxide (8.7 mL, 0.035 mole) was added. Stirring was continued as methyl isocyanate (0.97 g, 0.017 mole) in 5 mL diethyl ether was added dropwise. The mixture was filtered to yield 4.12 g (94.7%) N-methyl-1-dodecyl-hydrazinecarboxamide (m.p. 73°-75° C.). NMR analysis confirmed the structure.

Aufarbeitung

  1. customA stirred, degassed
  2. temperaturewas cooled under nitrogen
  3. additionwas added dropwise
  4. filtrationThe mixture was filtered

Quellen und Nachweise

ORD-Eintrag
ord-65043bcda5634aca90dd0bcf9f2fa99c
Quelldatensatz
uspto-grants-1985_06
Patentnummer
US04521325

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