3-Ethoxy-1-(3-pyridinyl)-2-propen-1-one → HCID 13475883, Verbindung

HRID 1247953

Reaktionsgleichung

Reaktionsgleichung von HRID 1247953
C(O[CH:4]=[CH:5][C:6]([C:8]1[CH:9]=[N:10][CH:11]=[CH:12][CH:13]=1)=O)C.[NH2:14][C:15]1[C:19]([C:20]([C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)=[O:21])=[CH:18][NH:17][N:16]=1>C1(C)C(C)=CC=CC=1>[C:22]1([C:20]([C:19]2[CH:18]=[N:17][N:16]3[C:6]([C:8]4[CH:9]=[N:10][CH:11]=[CH:12][CH:13]=4)=[CH:5][CH:4]=[N:14][C:15]=23)=[O:21])[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=1

Komponenten

4

Edukt 2

HCID 540323263-Ethoxy-1-(3-pyridinyl)-2-propen-1-oneHCID 178509267HCID 178509267, Verbindung

Produkt 1

HCID 13475883HCID 13475883, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 7237O-XyleneLösungsmittel

Versuchsvorschrift

A mixture of 0.02 mole of 3-ethoxy-1-(3-pyridinyl)-2-propen-1-one, 0.02 mole of (3-amino-1H-pyrazol-4-yl)phenyl-methanone and 100 ml of xylene was refluxed for 12 hours. The solvent was removed and the residue dissolved in dichloromethane. This solution was dried over sodium sulfate and the product isolated as described in Example 1, as crystals, mp 202°-203° C.

Aufarbeitung

  1. temperaturewas refluxed for 12 hours
  2. customThe solvent was removed
  3. dissolutionthe residue dissolved in dichloromethane
  4. dry with materialThis solution was dried over sodium sulfate
  5. customthe product isolated

Quellen und Nachweise

ORD-Eintrag
ord-c49638eb094243959a97d943725eda29
Quelldatensatz
uspto-grants-1985_06
Patentnummer
US04521422

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