N,N-Dimethylaniline → 1-Chloro-4-nitro-7-(phenylmethoxy)-9(10H)-acridinone

HRID 1248833Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1248833
[Cl:1][C:2]1[CH:10]=[CH:9][C:8]([N+:11]([O-:13])=[O:12])=[C:7]([NH:14][C:15]2[CH:20]=[CH:19][C:18]([O:21][CH2:22][C:23]3[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=3)=[CH:17][CH:16]=2)[C:3]=1[C:4](O)=[O:5].CN(C)C1C=CC=CC=1.P(Cl)(Cl)(Cl)=O>ClCCCl>[Cl:1][C:2]1[C:3]2[C:4](=[O:5])[C:20]3[C:15](=[CH:16][CH:17]=[C:18]([O:21][CH2:22][C:23]4[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=4)[CH:19]=3)[NH:14][C:7]=2[C:8]([N+:11]([O-:13])=[O:12])=[CH:9][CH:10]=1

Komponenten

5

Edukt 3

HCID 949N,N-DimethylanilineHCID 24813Phosphorus oxychlorideHCID 13588229HCID 13588229, Verbindung

Produkt 1

HCID 135883221-Chloro-4-nitro-7-(phenylmethoxy)-9(10H)-acridinone

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 111,2-DichloroethaneLösungsmittel

Versuchsvorschrift

Four grams of 2-chloro-5-nitro-6-[[4-(phenylmethoxy)phenyl]amino]benzoic acid was suspended in 80 ml of boiling 1,2-dichloroethane to which 0.2 ml of N,N-dimethylaniline was added followed by 8.0 ml of phosphorus oxychloride. The mixture was stirred under reflux for 30 minutes and cooled overnight. The resulting suspension was filtered providing the title compound as a red solid, mp 216°-217° C.

Aufarbeitung

  1. additionwas added
  2. temperatureunder reflux for 30 minutes
  3. temperaturecooled overnight
  4. filtrationThe resulting suspension was filtered

Quellen und Nachweise

ORD-Eintrag
ord-e7d21bc4d78845a6a4ba72571a10a7fd
Quelldatensatz
uspto-grants-1986_12
Patentnummer
US04626540

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