Oxalyl chloride → 2-(5-t-Butylfuran-2-yl)-cyclopropanecarbonyl chloride
Reaktionsgleichung
[C:1]([C:5]1[O:9][C:8]([CH:10]2[CH2:12][CH:11]2[C:13]([OH:15])=O)=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2].C(Cl)(=O)C([Cl:19])=O>CCCCCC>[C:1]([C:5]1[O:9][C:8]([CH:10]2[CH2:12][CH:11]2[C:13]([Cl:19])=[O:15])=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2]Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
A mixture of 2-(5-t-butylfuran-2-yl)-cyclopropanecarboxylic acid (3.6 g, 0.017 mol) and oxalyl chloride (4.4 g, 0.035 mol) in hexane (40 ml) was stirred at room temperature for 2 hours and then warmed at 60° C. for 3 hours. The hexane and excess oxalyl chloride were removed in vacuo to give 2-(5-t-butylfuran-2-yl)-cyclopropanecarbonyl chloride (3.9 g, 100%) as a pale yellow liquid which was used in the next stage without further purification.