Bromine → HCID 24765405, Verbindung

HRID 1255122

Reaktionsgleichung

Reaktionsgleichung von HRID 1255122
O1C2C=CC(C[C:11](Cl)=[O:12])=CC=2OC1.CO[C:16]1[CH:21]=[CH:20][C:19]([O:22]C)=[CH:18][C:17]=1[C:24]1[S:28][C:27]([NH:29][C:30](=[O:39])[C:31]2[C:36]([F:37])=[CH:35][CH:34]=[CH:33][C:32]=2[F:38])=[N:26][C:25]=1[CH3:40].[Br:41]Br>>[Br:41][C:21]1[C:20]2[O:12][CH2:11][O:22][C:19]=2[CH:18]=[C:17]([C:24]2[S:28][C:27]([NH:29][C:30](=[O:39])[C:31]3[C:36]([F:37])=[CH:35][CH:34]=[CH:33][C:32]=3[F:38])=[N:26][C:25]=2[CH3:40])[CH:16]=1

Komponenten

4

Edukt 3

HCID 24408BromineHCID 2756584Benzo[1,3]dioxol-5-yl-acetyl chlorideHCID 24765404N-(5-(2,5-Dimethoxyphenyl)-4-methylthiazol-2-yl)-2,6-difluorobenzamide

Produkt 1

HCID 24765405HCID 24765405, Verbindung

Versuchsvorschrift

Compound 56 was prepared from 2-(benzo[d][1,3]dioxol-5-yl)acetyl chloride in the similar manner as described for the preparation of Compound 55 with the exception that 2 equivalents of bromine was used.

Quellen und Nachweise

ORD-Eintrag
ord-4cbb285ef03145899b6a62dfe55242cb
Quelldatensatz
uspto-grants-2013_06
Patentnummer
US08455658B2

Verknüpfte Notizen

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