Methylamine → Benzenamine, N-methyl-2-nitro-4-(trifluoromethyl)-

HRID 1256611Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1256611
F[C:2]1[CH:7]=[CH:6][C:5]([C:8]([F:11])([F:10])[F:9])=[CH:4][C:3]=1[N+:12]([O-:14])=[O:13].[CH3:15][N:16]1CCCC1=O.CN>O>[CH3:15][NH:16][C:2]1[CH:7]=[CH:6][C:5]([C:8]([F:11])([F:10])[F:9])=[CH:4][C:3]=1[N+:12]([O-:14])=[O:13]

Komponenten

5

Edukt 3

HCID 6329MethylamineHCID 13387N-methyl-2-pyrrolidoneHCID 677784-Fluoro-3-nitrobenzotrifluoride

Produkt 1

HCID 88405Benzenamine, N-methyl-2-nitro-4-(trifluoromethyl)-

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

To a mixture of 2.09 g of 4-fluoro-3-nitrobenzo trifluoride and 20 ml of N-methylpyrrolidone was added 2.33 g of a 40% methylamine aqueous solution under ice cool, and the mixture was heated up to room temperature and stirred for 1 hour. Water was poured, and the deposited precipitate was filtrated, then, washed with water, then, dried under reduced pressure to obtain 2.0 g of N-methyl-2-nitro-4-trifluoromethylaniline.

Aufarbeitung

  1. temperaturecool
  2. filtrationthe deposited precipitate was filtrated
  3. washwashed with water
  4. customdried under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-4cebb6c7e28242d3911666207e4a27bd
Quelldatensatz
uspto-grants-2013_06
Patentnummer
US08461181B2

Notizen zur Reaktion

Wird geladen…