(+/-)-2-Cyclopropyl-1-methoxybut-3-yn-2-ol → (+/-)-2-Amino-7-(3-cyclopropyl-3-hydroxy-4-methoxybut-1-yn-1-yl)-1-ethyl-N-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxamide
Reaktionsgleichung
[NH2:1][C:2]1[N:3]([CH2:18][CH3:19])[C:4]2[C:9]([C:10](=[O:16])[C:11]=1[C:12]([NH:14][CH3:15])=[O:13])=[CH:8][CH:7]=[C:6](Cl)[N:5]=2.[CH:20]1([C:23]([OH:29])([C:27]#[CH:28])[CH2:24][O:25][CH3:26])[CH2:22][CH2:21]1>CN(C)C=O.C(N(CC)CC)C.[Cu]I.C1C=CC(P(C2C=CC=CC=2)C2C=CC=CC=2)=CC=1.C1C=CC(P(C2C=CC=CC=2)C2C=CC=CC=2)=CC=1.Cl[Pd]Cl>[NH2:1][C:2]1[N:3]([CH2:18][CH3:19])[C:4]2[C:9]([C:10](=[O:16])[C:11]=1[C:12]([NH:14][CH3:15])=[O:13])=[CH:8][CH:7]=[C:6]([C:28]#[C:27][C:23]([CH:20]1[CH2:22][CH2:21]1)([OH:29])[CH2:24][O:25][CH3:26])[N:5]=2Komponenten
7
