3-Aminobenzoic Acid → 3-[(3-Ethoxyacryloyl)amino]benzoic acid

HRID 1262838

Reaktionsgleichung

Reaktionsgleichung von HRID 1262838
[NH2:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][CH:10]=1)[C:5]([OH:7])=[O:6].[CH2:11]([O:13][CH:14]=[CH:15][C:16](Cl)=[O:17])[CH3:12]>C(OCC)C>[C:5]([C:4]1[CH:3]=[C:2]([CH:10]=[CH:9][CH:8]=1)[NH:1][C:16](=[O:17])[CH:15]=[CH:14][O:13][CH2:11][CH3:12])([OH:7])=[O:6]

Komponenten

4

Edukt 2

HCID 74193-Aminobenzoic AcidHCID 30144293-Ethoxy-2-propenoyl chloride

Produkt 1

HCID 545354873-[(3-Ethoxyacryloyl)amino]benzoic acid

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 3283Diethyl EtherLösungsmittel

Reaktionsbedingungen

Temperatur
40 °C

Versuchsvorschrift

100 Grams of m-aminobenzoic acid was suspended in 1 liter of diethyl ether, and at a room temperature with stirring 44.6 g of β-ethoxyacrylic chloride was added dropwise. Then the reaction mixture was heated at 40° C. for 5 hours. After the reaction was completed, the precipitated matter was collected by filtration and washed with water three times, and dried, and recrystallized from methanol to obtain 60 g of m-carboxy-N-(β-ethoxyacryloyl)aniline.

Aufarbeitung

  1. additionwas added dropwise
  2. filtrationthe precipitated matter was collected by filtration
  3. washwashed with water three times
  4. customdried
  5. customrecrystallized from methanol

Quellen und Nachweise

ORD-Eintrag
ord-6923eac52f6f4843a372aefd8d1a0b14
Quelldatensatz
uspto-grants-1984_06
Patentnummer
US04454130

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