Hydrogen Bromide → 2-(Bromomethyl)-4-methyl-1-nitrobenzene
Reaktionsgleichung
[BrH:1].[CH3:2][C:3]1[CH:4]=[CH:5][C:6]([N+:11]([O-:13])=[O:12])=[C:7]([CH:10]=1)[CH2:8]O>C(O)(=O)C>[CH3:2][C:3]1[CH:4]=[CH:5][C:6]([N+:11]([O-:13])=[O:12])=[C:7]([CH:10]=1)[CH2:8][Br:1]Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
To a cooled (ice-water bath) mixture of 30% HBr in acetic acid (3 ml) was added 2.5 g 5-methyl-2-nitrobenzyl alcohol and the chilled solution stirred for 2 hours. The mixture was poured into ice-water and extracted with diethyl ether. The extract was washed with H2O, brine and the solvent removed under vacuum to give a mixture of product (50%) and starting material (50%).
Aufarbeitung
- temperatureTo a cooled
- extractionextracted with diethyl ether
- washThe extract was washed with H2O, brine
- customthe solvent removed under vacuum
- customto give
Quellen und Nachweise
- ORD-Eintrag
- ord-5ee68db543654f1f8a74c0e4c242249e
- Quelldatensatz
- uspto-grants-2003_04
- Patentnummer
- US06544984B1
Notizen zur Reaktion
Wird geladen…