Hydrazine hydrate (1:1) → HCID 18544800, Verbindung

HRID 1266928Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1266928
F[C:2]1[C:7]([C:8]([F:11])([F:10])[F:9])=[C:6]([O:12][CH3:13])[N:5]=[C:4]([CH3:14])[N:3]=1.O.[NH2:16][NH2:17]>C(O)C>[NH:16]([C:2]1[C:7]([C:8]([F:11])([F:10])[F:9])=[C:6]([O:12][CH3:13])[N:5]=[C:4]([CH3:14])[N:3]=1)[NH2:17]

Komponenten

4

Edukt 2

HCID 24654Hydrazine hydrate (1:1)HCID 133793024-Fluoro-6-methoxy-2-methyl-5-(trifluoromethyl)pyrimidine

Produkt 1

HCID 18544800HCID 18544800, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

Next, a reaction flask was loaded with 4-fluoro-6-methoxy-2-methyl-5-(trifluoromethyl)-pyrimidine (22 g) and ethanol (40 ml), followed by dropwise addition of hydrazine monohydrate (10.5 g) to the flask in one hour with stirring. Then, after stirring for one hour, the reaction mixture was filtrated to give 4-hydrazino-6-methoxy-2-methyl-5-(trifluoromethyl)pyrimidine. By GC/MS analysis, a molecular ion peak of 222 was confirmed for this compound.

Aufarbeitung

  1. stirringThen, after stirring for one hour
  2. filtrationthe reaction mixture was filtrated

Quellen und Nachweise

ORD-Eintrag
ord-ef40c0aa281a4cbc8861ef1eea4bd4f1
Quelldatensatz
uspto-grants-2003_04
Patentnummer
US06551682B1

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