Acetic Anhydride → HCID 20529234, Verbindung

HRID 126896Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 126896
[CH3:1][NH:2][CH:3]1[CH2:15][CH2:14][C:13]2[C:12]3[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=3)[NH:6][C:5]=2[CH2:4]1.C(O[C:20](=[O:22])[CH3:21])(=O)C>>[CH2:4]1[C:5]2[NH:6][C:7]3[C:12](=[CH:11][CH:10]=[CH:9][CH:8]=3)[C:13]=2[CH2:14][CH2:15][CH:3]1[N:2]([CH3:1])[C:20](=[O:22])[CH3:21]

Komponenten

3

Edukt 2

HCID 7918Acetic AnhydrideHCID 20529239HCID 20529239, Verbindung

Produkt 1

HCID 20529234HCID 20529234, Verbindung

Versuchsvorschrift

A mixture of 10.0 g (0.05 mol) of 2,3,4,9-tetrahydro-N-methyl-1H-carbazol-2-amine and 70 ml of acetic anhydride was heated at reflux until complete solution occurred (2-3 min). After standing overnight at room temperature and further cooling at 0°, the precipitated solid was filtered, washed first with small portions of cold acetic anhydride and then thoroughly with anhydrous ether. The crude product was recrystallized from ethanol to give the title compound, mp 215°-216°.

Aufarbeitung

  1. temperaturewas heated
  2. temperatureat reflux until complete solution
  3. custom(2-3 min)
  4. temperaturefurther cooling at 0°
  5. filtrationthe precipitated solid was filtered
  6. washwashed first with small portions of cold acetic anhydride
  7. customThe crude product was recrystallized from ethanol

Quellen und Nachweise

ORD-Eintrag
ord-04450d90296e48e4801f9a0315f6a30c
Quelldatensatz
uspto-grants-1981_03
Patentnummer
US04254134

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