Acetic Anhydride → (4-Nitropyridin-2-yl)methyl acetate

HRID 1270044Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1270044
[C:1]([O:4][C:5](=[O:7])[CH3:6])(=O)[CH3:2].CC1[CH:14]=[C:13]([N+:15]([O-:17])=[O:16])[CH:12]=[CH:11][N+:10]=1[O-]>C(O)C>[C:5]([O:4][CH2:1][C:2]1[CH:14]=[C:13]([N+:15]([O-:17])=[O:16])[CH:12]=[CH:11][N:10]=1)(=[O:7])[CH3:6]

Komponenten

4

Edukt 2

HCID 7918Acetic AnhydrideHCID 95291Pyridine, 2-methyl-4-nitro-, 1-oxide

Produkt 1

HCID 14761430(4-Nitropyridin-2-yl)methyl acetate

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Reaktionsbedingungen

Temperatur
80 °C

Versuchsvorschrift

200 mL of acetic anhydride was heated to 100° C., followed by gradual addition of 2-methyl-4-nitropyridine N-oxide (25.0 g, 162 mmol). After the addition, the mixture was gradually heated, and was kept at 130° C. for 20 minutes. Then, the reaction mixture was cooled to 80° C., followed by dropwise addition of 200 mL of ethanol to stop the reaction.

Aufarbeitung

  1. additionAfter the addition
  2. temperaturethe mixture was gradually heated
  3. customthe reaction

Quellen und Nachweise

ORD-Eintrag
ord-0458662f3c914a128d06582f9b9f9852
Quelldatensatz
uspto-grants-2007_04
Patentnummer
US07202093B2

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