Acetone → HCID 21707621, Verbindung

HRID 1275950Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1275950
[CH3:1][C:2]12[CH2:7][CH:6]1[CH2:5][CH:4]([CH2:8][CH:9]1OCC[O:10]1)[C:3]2([CH3:15])[CH3:14].CC(C)=O.Cl>O>[CH3:1][C:2]12[CH2:7][CH:6]1[CH2:5][CH:4]([CH2:8][CH:9]=[O:10])[C:3]2([CH3:15])[CH3:14]

Komponenten

5

Edukt 3

HCID 180AcetoneHCID 313Hydrochloric AcidHCID 21707623HCID 21707623, Verbindung

Produkt 1

HCID 21707621HCID 21707621, VerbindungAusbeute 79 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

A mixture of 11.0 g (52 mmol) of 2-(1,2,2-trimethylbicyclo[3.1.0]hex-3-ylmethyl)-[1,3]-dioxolane, 80 ml of acetone, 40 ml of water, 1.5 ml of conc. hydrochloric acid and 10 g of silica gel was stirred at reflux for 4 hours. After filtration, the solution was diluted with diethyl ether, washed with water, dried (MgSO4) and evaporated in vacuo. Kugelrohr distillation of the residue gave 6.8 g (79% yield) of (1,2,2-trimethylbicyclo[3.1.0]hex-3-yl)ethanal.

Aufarbeitung

  1. temperatureat reflux for 4 hours
  2. filtrationAfter filtration
  3. additionthe solution was diluted with diethyl ether
  4. washwashed with water
  5. dry with materialdried (MgSO4)
  6. customevaporated in vacuo
  7. distillationKugelrohr distillation of the residue

Quellen und Nachweise

ORD-Eintrag
ord-99cae8c6ddb2499dbd31f10da6c87b0e
Quelldatensatz
uspto-grants-2000_12
Patentnummer
US06162954

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