Butanethiol → HCID 20285387, Verbindung

HRID 127659Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 127659
[CH2:1]([SH:5])[CH2:2][CH2:3][CH3:4].[H-].[Na+].Cl[CH:9]([C:16]1[CH:21]=[CH:20][C:19]([Cl:22])=[CH:18][C:17]=1[Cl:23])[CH2:10][N:11]1[CH:15]=[N:14][CH:13]=[N:12]1>O1CCCC1>[CH2:1]([S:5][CH:9]([C:16]1[CH:21]=[CH:20][C:19]([Cl:22])=[CH:18][C:17]=1[Cl:23])[CH2:10][N:11]1[CH:15]=[N:14][CH:13]=[N:12]1)[CH2:2][CH2:3][CH3:4]

Komponenten

5

Edukt 3

HCID 8012ButanethiolHCID 24758Sodium hydrideHCID 134886161-[2-Chloro-2-(2,4-dichlorophenyl)ethyl]-1H-1,2,4-triazole

Produkt 1

HCID 20285387HCID 20285387, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8028TetrahydrofuranLösungsmittel2×

Versuchsvorschrift

12.55 parts by weight of butylmercaptan is dripped into a suspension of 3.33 parts by weight of sodium hydride in 180 parts by weight of tetrahydrofuran. A solution of 27.5 parts by weight of 1-[2-chloro-2-(2,4-dichlorophenyl)-ethyl]-1,2,4-triazole in 50 parts of tetrahydrofuran is then dripped in and the mixture is stirred for 3 days at room temperature. The mixture is concentrated, stirred with water, and extracted with dichloromethane. The resulting dichloromethane solution is dried and evaporated. There is obtained 29.5 parts of crude 1-[2-n-butylmercapto-2-(2,4-dichlorophenyl)-ethyl]-1,2,4-triazole, which is dissolved in ethyl acetate. When hydrogen chloride is passed into the ethyl acetate solution, 25.9 parts of 1-[2-n-butylmercapto-2-(2,4-dichlorophenyl)-ethyl]-1,2,4-triazole hydrochloride, m.p. 143° C., precipitates out.

Aufarbeitung

  1. concentrationThe mixture is concentrated
  2. stirringstirred with water
  3. extractionextracted with dichloromethane
  4. dry with materialThe resulting dichloromethane solution is dried
  5. customevaporated

Quellen und Nachweise

ORD-Eintrag
ord-01a85a6c040c4d478281a98218ad40d8
Quelldatensatz
uspto-grants-1981_03
Patentnummer
US04256754

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