Acetic Acid → HCID 12875270, Verbindung
Reaktionsgleichung
C=O.[ClH:3].[CH3:4][C:5]1[S:6][C:7]([Cl:11])=[CH:8][C:9]=1[Cl:10].[C:12](O)(=O)C>>[Cl:3][CH2:12][C:8]1[C:9]([Cl:10])=[C:5]([CH3:4])[S:6][C:7]=1[Cl:11]Komponenten
5
Reaktionsbedingungen
- Temperatur
- 70 °C
Versuchsvorschrift
8.6 G. (0.107 mol) of formalin and 90 ml. concentrated hydrochloric acid were added to a solution of 10.87 g. (0.065 mol) of 2-methyl-3,5-dichlorothiophene in 45 ml. of acetic acid. The resulting mixture was heated to 70° C. for 18 hrs., cooled, poured into ice water and extracted with ether. The organic solution was washed with water, sodium bicarbonate and water, dried and evaporated to yield 3-chloromethyl-2,4-dichloro-5-methylthiophene as a crude oil.
Aufarbeitung
- temperature, cooled
- extractionextracted with ether
- washThe organic solution was washed with water, sodium bicarbonate and water
- customdried
- customevaporated
Quellen und Nachweise
- ORD-Eintrag
- ord-59880102164842b0b46f14d333a3894d
- Quelldatensatz
- uspto-grants-1981_03
- Patentnummer
- US04256878
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