Sodium Carbonate → HCID 23452138, Verbindung

HRID 1277878Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1277878
Cl.Cl.[CH3:3][N:4]([CH2:6][C:7]1[O:11][C:10]([CH2:12][S:13][CH2:14][CH2:15][NH2:16])=[CH:9][CH:8]=1)[CH3:5].[O-:17][C:18]#[N:19].[K+].C(=O)([O-])[O-].[Na+].[Na+]>O>[CH3:5][N:4]([CH2:6][C:7]1[O:11][C:10]([CH2:12][S:13][CH2:14][CH2:15][NH:16][C:18]([NH2:19])=[O:17])=[CH:9][CH:8]=1)[CH3:3]

Komponenten

5

Edukt 3

HCID 10340Sodium CarbonateHCID 11378442Potassium cyanateHCID 189238085-{[(2-Aminoethyl)-thio]-methyl}-N,N-dimethyl-2-furanmethanamine dihydrochl

Produkt 1

HCID 23452138HCID 23452138, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

A solution of 2-[[[5-(dimethylamino)methyl-2-furanyl]methyl]thio]ethanamine dihydrochloride (2.8 g) and potassium cyanate (3.75 g) in water (50 ml) was heated on a steam bath for 8 hr. Excess solid sodium carbonate was added and organic material continually extracted with diethyl ether. The extracts were evaporated and the residue after column chromatography yielded N-[2-[[[5-(dimethylamino)methyl-2-furanyl]methyl]thio]ethyl]urea as a waxy solid (1.28 g). Analysis Found: C, 48.22; H, 7.50; N, 15.61. C11H19N3O2S.H2O requires: C, 48.00; H, 7.63; N, 15.27%.

Aufarbeitung

  1. extractionorganic material continually extracted with diethyl ether
  2. customThe extracts were evaporated

Quellen und Nachweise

ORD-Eintrag
ord-97ed4bf7676e46e8abb7dc14e13011c7
Quelldatensatz
uspto-grants-1981_07
Patentnummer
US04279819

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