HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-(4-Nitrobenzyl)-1-methylpyrrolidine → 4-[(1-Methylpyrrolidin-2-yl)methyl]aniline
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-(4-Nitrobenzyl)-1-methylpyrrolidine | HCID 13186905 | — |
| Katalysator | HCID 178506448 | HCID 178506448 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Produkt | 4-[(1-Methylpyrrolidin-2-yl)methyl]aniline | HCID 13186904 | — |
Reaktionsschritte
Hydrogenate 18 g of 2-(4-nitrobenzyl)-1-methylpyrrolidine in ethanol with 300 mg of platinum dioxide/hydrogen. Filter the catalyst from the reaction mixture, concentrate the latter and recrystallize the thus-produced residue from n-hexane to obtain the title compound at a yield of 12.7 g (82% of theory).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04279918 |
| Quelldatensatz | uspto-grants-1981_07 |
| ORD ID | ord-1cb7867abf4a4a23b6ea281998cc6f6b |
| Quellennotiz | uspto-grants-1981_07 |