反应详情

Hydrogenate 18 g of 2-(4-nitrobenzyl)-1-methylpyrrolidine in ethanol with 300 mg of platinum dioxide/hydrogen. Filter the catalyst from the reaction mixture, concentrate the latter and recrystallize the thus-produced residue from n-hexane to obtain the title compound at a yield of 12.7 g (82% of theory).

1. filtrationFilter the catalyst from the reaction mixture
2. concentrationconcentrate the latter and
3. customrecrystallize the thus-produced residue from n-hexane