N,O-Dimethylhydroxylamine → N'-[4-(2-naphthyloxy)phenyl]-N-methoxy-N-methylurea

HRID 1278162Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1278162
[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[O:11][C:12]1[CH:17]=[CH:16][C:15]([N:18]=[C:19]=[O:20])=[CH:14][CH:13]=1.[CH3:21][NH:22][O:23][CH3:24]>C1C=CC=CC=1>[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[O:11][C:12]1[CH:17]=[CH:16][C:15]([NH:18][C:19](=[O:20])[N:22]([O:23][CH3:24])[CH3:21])=[CH:14][CH:13]=1

Komponenten

4

Edukt 2

HCID 14232N,O-DimethylhydroxylamineHCID 127740664-(2-Naphthyloxy)phenyl isocyanate

Produkt 1

HCID 12893343N'-[4-(2-naphthyloxy)phenyl]-N-methoxy-N-methylureaAusbeute 87,3 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 241BenzeneLösungsmittel2×

Versuchsvorschrift

Thirteen grams of 4-(2-naphthyloxy)phenyl isocyanate were dissolved in 100 ml of benzene, and a solution of 4 g of N,O-dimethylhydroxylamine in 50 ml of benzene was added dropwise thereto at a temperature below 30° C. The reaction mixture was allowed to stand at room temperature for 30 minutes, and the solvent was then removed under reduced pressure. The residue was recrystallized from ethanol to obtain 14 g of N'-[4-(2-naphthyloxy)phenyl]-N-methoxy-N-methylurea as white needles. M.P., 102°-103° C.

Aufarbeitung

  1. customat a temperature below 30° C
  2. customthe solvent was then removed under reduced pressure
  3. customThe residue was recrystallized from ethanol

Quellen und Nachweise

ORD-Eintrag
ord-00fa8abd9f3042a093cef9b96ed85e8a
Quelldatensatz
uspto-grants-1981_07
Patentnummer
US04280835

Notizen zur Reaktion

Wird geladen…