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Hydrochloric Acid → 2,4-Imidazolidinedione, 5-(4-methoxy-3-methylphenyl)-5-(4-methoxyphenyl)-

HRID 1278255
Notizen
Druckvorschau

Reaktionsgleichung

Reaktionsgleichung von HRID 1278255
[CH3:1][O:2][C:3]1[CH:18]=[CH:17][C:6]([C:7]([C:9]2[CH:14]=[CH:13][C:12]([O:15][CH3:16])=[CH:11][CH:10]=2)=O)=[CH:5][C:4]=1[CH3:19].[C-]#[N:21].[K+].[C:23](=[O:26])([O-])O.[NH4+].[CH:28]([NH2:30])=[O:29].Cl>O>[CH3:1][O:2][C:3]1[CH:18]=[CH:17][C:6]([C:7]2([C:9]3[CH:14]=[CH:13][C:12]([O:15][CH3:16])=[CH:11][CH:10]=3)[NH:21][C:28](=[O:29])[NH:30][C:23]2=[O:26])=[CH:5][C:4]=1[CH3:19]
KomponentenVersuchsvorschriftAufarbeitungQuellen und NachweiseNotizen zur Reaktion

Komponenten

7

Edukt 5

HCID 313Hydrochloric AcidHCID 713FormamideHCID 9032Potassium CyanideHCID 14013Ammonium BicarbonateHCID 19864229HCID 19864229, Verbindung

Produkt 1

HCID 30581982,4-Imidazolidinedione, 5-(4-methoxy-3-methylphenyl)-5-(4-methoxyphenyl)-

Reagenzien, Katalysatoren, Lösungsmittel

1
HCID 962WaterLösungsmittel2×

Versuchsvorschrift

34.5 Grams of 4,4'-dimethoxy-3-methylbenzophenone, 66.7 g of potassium cyanide and 232.2 g of ammonium hydrogencarbonate were heated to 120° C. together with 500 ml. of formamide and 100 ml. of water with stirring in an autoclave. After 72 hours, the reaction liquid was made acidic with concentrated hydrochloric acid, mixed with water and allowed to stand overnight. The precipitates thus formed were filtered out. The precipitates were dissolved in acetone, decolorized by active carbon under heating and recrystallized from hexane-acetone to obtain 22.7 g of 5-(4-methoxy-3-methylphenyl)-5-(4-methoxyphenyl)-hydantoin in the form of white crystals.

Aufarbeitung

  1. customthe reaction liquid
  2. waitto stand overnight
  3. customThe precipitates thus
  4. customformed
  5. filtrationwere filtered out
  6. dissolutionThe precipitates were dissolved in acetone
  7. temperatureunder heating
  8. customrecrystallized from hexane-acetone

Quellen und Nachweise

ORD-Eintrag
ord-676d664ae2ee41bc83bcef77a20d934f
Quelldatensatz
uspto-grants-1981_07
DOI
10.6084/m9.figshare.5104873.v1
Patentnummer
US04281009

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