Hydrochloric Acid → 5,5-Bis(4-hydroxyphenyl)hydantoin

HRID 1278256Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1278256
[OH:1][C:2]1[CH:16]=[CH:15][C:5]([C:6]([C:8]2[CH:13]=[CH:12][C:11]([OH:14])=[CH:10][CH:9]=2)=O)=[CH:4][CH:3]=1.[C-]#[N:18].[K+].[C:20](=[O:23])([O-])[O-].[NH4+].[NH4+].[CH:26]([NH2:28])=[O:27].Cl>O>[OH:1][C:2]1[CH:16]=[CH:15][C:5]([C:6]2([C:8]3[CH:13]=[CH:12][C:11]([OH:14])=[CH:10][CH:9]=3)[NH:18][C:26](=[O:27])[NH:28][C:20]2=[O:23])=[CH:4][CH:3]=1

Komponenten

7

Edukt 5

HCID 313Hydrochloric AcidHCID 713FormamideHCID 9032Potassium CyanideHCID 691504,4'-DihydroxybenzophenoneHCID 517111Ammonium Carbonate

Produkt 1

HCID 1488755,5-Bis(4-hydroxyphenyl)hydantoin

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel2×

Versuchsvorschrift

100 Grams of 4,4'-dihydroxybenzophenone, 152.1 g of potassium cyanide and 426.3 g of ammonium carbonate were heated to 120° C. together with 750 ml. of formamide and 150 ml. of water with stirring in an autoclave for 48 hours. The reaction liquid was made acidic with concentrated hydrochloric acid, mixed with water and allowed to stand overnight. The precipitates thus formed were filtered out. The precipitates were decolorized by active carbon and recrystallized from 50% methanol to obtain 111.4 g of 5,5-bis(4-hydroxyphenyl)hydantoin in the form of white crystals.

Aufarbeitung

  1. customThe reaction liquid
  2. customThe precipitates thus
  3. customformed
  4. filtrationwere filtered out
  5. customrecrystallized from 50% methanol

Quellen und Nachweise

ORD-Eintrag
ord-e76319feab26461eaadea0e8e0d9208d
Quelldatensatz
uspto-grants-1981_07
Patentnummer
US04281009

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