Acetic Anhydride → (3,4,8-trimethyl-2-oxochromen-7-yl) acetate

HRID 1281641Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1281641
[OH:1][C:2]1[C:11]([CH3:12])=[C:10]2[C:5]([C:6]([CH3:15])=[C:7]([CH3:14])[C:8](=[O:13])[O:9]2)=[CH:4][CH:3]=1.[C:16](OC(=O)C)(=[O:18])[CH3:17]>>[C:16]([O:1][C:2]1[C:11]([CH3:12])=[C:10]2[C:5]([C:6]([CH3:15])=[C:7]([CH3:14])[C:8](=[O:13])[O:9]2)=[CH:4][CH:3]=1)(=[O:18])[CH3:17]

Komponenten

3

Edukt 2

HCID 7918Acetic AnhydrideHCID 53971957-Hydroxy-3,4,8-trimethylcoumarin

Produkt 1

HCID 854734(3,4,8-trimethyl-2-oxochromen-7-yl) acetate

Versuchsvorschrift

A solution of 7-hydroxy-3,4,8-trimethylcoumarin (5.19 g, 25.4 mmol) was refluxed in acetic anhydride (10 mL) for 1.5 hours. The solution was slowly poured into ice water (200 mL) and the resulting solid was filtered, then rinsed with water to yield 7-acetoxy-3,4,8-trimethylcoumarin, a beige solid (6.22 g, 99.5%). 1H NMR (CDCl3): δ7.47 (d, J=8.6 Hz, 1H), 7.00 (d, J=8.7 Hz, 1H), 2.40 (s, 3H), 2.37 (s, 3H), 2.29 (s, 3H), 2.22 (s, 3H).

Aufarbeitung

  1. filtrationthe resulting solid was filtered
  2. washrinsed with water

Quellen und Nachweise

ORD-Eintrag
ord-7161f90df0a74543adb054722fe95f24
Quelldatensatz
uspto-grants-2002_09
Patentnummer
US06455286B1

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