Phosphorus pentachloride → 2-Chlorocarbonyl-6-methyl-benzo[b] thiophene-3-sulfonic acid chloride

HRID 128281Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 128281
[C:1]([C:4]1[S:8][C:7]2[CH:9]=[C:10]([CH3:13])[CH:11]=[CH:12][C:6]=2[C:5]=1[S:14]([O-:17])(=O)=[O:15])(O)=[O:2].[Na+].P(Cl)(Cl)(Cl)(Cl)Cl.[Cl-:25].[Cl-:26].[Cl-].[P+3]=O>>[Cl:25][C:1]([C:4]1[S:8][C:7]2[CH:9]=[C:10]([CH3:13])[CH:11]=[CH:12][C:6]=2[C:5]=1[S:14]([Cl:26])(=[O:17])=[O:15])=[O:2]

Komponenten

4

Edukt 3

HCID 24819Phosphorus pentachlorideHCID 86737645Monosodium 2-carboxy-6-methyl-benzo[b] thiophene-3-sulfonateHCID 178527001HCID 178527001, Verbindung

Produkt 1

HCID 538745162-Chlorocarbonyl-6-methyl-benzo[b] thiophene-3-sulfonic acid chlorideAusbeute 82 %

Versuchsvorschrift

Prepared analogous to Example 1(b) from monosodium 2-carboxy-6-methyl-benzo[b] thiophene-3-sulfonate and phosphorus-(V)-chloride in the presence of phosphorus oxide trichloride with a yield of 82% of theory. The product, which crystallized upon cooling, was used in the next step without further purification.

Aufarbeitung

  1. customThe product, which crystallized
  2. temperatureupon cooling
  3. customwas used in the next step without further purification

Quellen und Nachweise

ORD-Eintrag
ord-9f28a53b1eba47459e14931769153081
Quelldatensatz
uspto-grants-1981_03
Patentnummer
US04259336

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