Boron trifluoride → HCID 13588518, Verbindung

HRID 1284441Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1284441
[C:1]([OH:16])(=[O:15])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][C:7]#[C:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14].B(F)(F)F>C(O)(CC)C.CCOCC>[C:1]([O:16][CH:2]([CH2:3][CH3:4])[CH3:1])(=[O:15])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][C:7]#[C:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14]

Komponenten

5

Edukt 2

HCID 6356Boron trifluorideHCID 53127097-Tetradecynoic acid

Produkt 1

HCID 13588518HCID 13588518, VerbindungAusbeute 170,5 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 3283Diethyl EtherLösungsmittelHCID 6568(+-)-2-ButanolLösungsmittel

Versuchsvorschrift

A solution of 7-tetradecynoic acid (1.22 g) and BF3 -etherate (1 ml) in 20 ml of sec-butyl alcohol was refluxed for 18 hours. The solution was diluted with ether and washed with saturated Na2CO3 solution, water, 2N NaOH, water, and saturated NH4Cl solution. The ether layer was dried (MgSO4) and the solvent removed under reduced pressure to give 1.30 g of sec-butyl 7-tetradecynoate as a yellow liquid.

Aufarbeitung

  1. washwashed with saturated Na2CO3 solution, water, 2N NaOH, water, and saturated NH4Cl solution
  2. dry with materialThe ether layer was dried (MgSO4)
  3. customthe solvent removed under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-0ae7ca54a92c4c50b37642c9ed474bc5
Quelldatensatz
uspto-grants-1986_01
Patentnummer
US04563348

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