StartseiteMCPWorkbenchSkills
StartseiteWorkbenchBenachrichtigungenMein Bereich
llms.txt · MCP-AnleitungDatenschutz · Nutzungsbedingungen · Supportv1.8.0
  1. Startseite
  2. /Reaktion

3-(4-Aminophenyl)-1-(4-methylphenyl)propan-1-one → 3-(4-aminophenyl)-1-(4-methylphenyl)propan-1-ol

HRID 1285278
Notizen
Druckvorschau

Reaktionsgleichung

Reaktionsgleichung von HRID 1285278
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=[O:18])[CH2:9][CH2:10][C:11]2[CH:16]=[CH:15][C:14]([NH2:17])=[CH:13][CH:12]=2)=[CH:4][CH:3]=1.[H][H]>O1CCCC1.[Pd]>[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([OH:18])[CH2:9][CH2:10][C:11]2[CH:12]=[CH:13][C:14]([NH2:17])=[CH:15][CH:16]=2)=[CH:4][CH:3]=1
KomponentenVersuchsvorschriftAufarbeitungQuellen und NachweiseNotizen zur Reaktion

Komponenten

5

Edukt 2

HCID 27682673-(4-Aminophenyl)-1-(4-methylphenyl)propan-1-oneHCID 178418361HCID 178418361, Verbindung

Produkt 1

HCID 43137463-(4-aminophenyl)-1-(4-methylphenyl)propan-1-ol

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 8028TetrahydrofuranLösungsmittel

Versuchsvorschrift

60 g of the 1-(4-methylphenyl)-3-(4-aminophenyl)-n-propan-1-one prepared as described in Example A were hydrogenated, in 1 liter of tetrahydrofuran, in the presence of 5 g of 10% strength Pd on charcoal, under 1.1 bar, until 5.5 liters of hydrogen had been absorbed. The catalyst was separated off and the reaction solution was evaporated down, and the oil obtained crystallized on trituration with diisopropyl ether. After the white crystals had been dried, 53 g (88% of theory) of the carbinol of melting point 63°-65° C. were obtained.

Aufarbeitung

  1. customhad been absorbed
  2. customThe catalyst was separated off
  3. customthe reaction solution was evaporated down
  4. customthe oil obtained
  5. customcrystallized on trituration with diisopropyl ether
  6. customAfter the white crystals had been dried
  7. custom53 g (88% of theory) of the carbinol of melting point 63°-65° C. were obtained

Quellen und Nachweise

ORD-Eintrag
ord-16f89062146b4684aa3f9195002e85bc
Quelldatensatz
uspto-grants-1986_01
DOI
10.6084/m9.figshare.5104873.v1
Patentnummer
US04566900

Notizen zur Reaktion

Wird geladen…

Auf dieser SeiteKomponentenVersuchsvorschriftAufarbeitungQuellen und NachweiseNotizen zur Reaktion