Trimethylsilyl iodide → 207669-62-3

HRID 1289349

Reaktionsgleichung

Reaktionsgleichung von HRID 1289349
C[O:2][CH:3]1[CH2:8][CH2:7][CH:6]([CH2:9][Br:10])[CH2:5][CH2:4]1.C[Si](I)(C)C>C(Cl)(Cl)Cl>[Br:10][CH2:9][CH:6]1[CH2:7][CH2:8][CH:3]([OH:2])[CH2:4][CH2:5]1

Komponenten

4

Edukt 2

HCID 85247Trimethylsilyl iodideHCID 217065291-(Bromomethyl)-4-methoxycyclohexane

Produkt 1

HCID 21832707207669-62-3

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6212ChloroformLösungsmittel

Versuchsvorschrift

The 4-methoxycyclohexylbromomethane compound (C-4) (2.6 g) in chloroform (7.8 g) was cooled with ice. Then trimethylsilyliodide (2.2 ml) was transferred to the C-4 solution. It was stirred at ambient temperature for 8 h, and then quenched with methanol. Then, volatiles were removed to obtain the desired alcohol in almost quantitative yield.

Aufarbeitung

  1. customquenched with methanol
  2. customThen, volatiles were removed

Quellen und Nachweise

ORD-Eintrag
ord-7df562be99754e0aaf4e0a7c5c27f733
Quelldatensatz
uspto-grants-1998_05
Patentnummer
US05750300

Verknüpfte Notizen

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