Ammonia → HCID 178508172, Verbindung

HRID 1292479

Reaktionsgleichung

Reaktionsgleichung von HRID 1292479
Cl[C:2]1[C:11]2[N:12]=[CH:13][NH:14][C:10]=2[C:9]2[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=2[N:3]=1.[NH3:15]>CO>[NH:14]1[C:10]2[C:9]3[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=3[N:3]=[C:2]([NH2:15])[C:11]=2[N:12]=[CH:13]1

Komponenten

4

Edukt 2

HCID 222AmmoniaHCID 178478309HCID 178478309, Verbindung

Produkt 1

HCID 178508172HCID 178508172, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel

Versuchsvorschrift

Using the method of Example 6, the product of Example 18, 0.2 g (0.0010 mole) of 4-chloro-1H-imidazo[4,5-c]quinoline was aminated at 175° C. in 12% ammonia in methanol to provide 1H-imidazo[4,5-c]quinolin-4-amine. The structure was verified by comparison of infrared and nuclear magnetic resonance spectra of the product with spectra of the product from Example 23.

Quellen und Nachweise

ORD-Eintrag
ord-9c4927f095e64bba899e764604c4df71
Quelldatensatz
uspto-grants-1998_05
Patentnummer
US05756747

Verknüpfte Notizen

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