Sodium borohydride → HCID 69507792, Verbindung

HRID 1295737Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1295737
[CH3:1][N:2]=[CH:3][C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([O:10][CH2:11][S:12][CH3:13])[CH:5]=1.[BH4-].[Na+]>CCO>[CH3:1][NH:2][CH2:3][C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([O:10][CH2:11][S:12][CH3:13])[CH:5]=1

Komponenten

4

Edukt 2

HCID 4311764Sodium borohydrideHCID 69507905828242-89-3

Produkt 1

HCID 69507792HCID 69507792, VerbindungAusbeute 57 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Reaktionsbedingungen

Temperatur
0 °C

Versuchsvorschrift

Compound from step 2 (3.546 g, 18.16 mmol) was dissolved in EtOH (50 mL) and cooled to 0° C. NaBH4 (859 mg, 22.70 mmol) was added and the mixture was allowed to stir for 4 h. The reaction was carefully quenched with water. The EtOH was removed in vacuo. The aqueous residue was extracted with CH2Cl2. The organic extracts were dried over Na2SO4 and concentrated in vacuo to give 2.044 g (57%) of a clear yellow oil.

Aufarbeitung

  1. customThe reaction was carefully quenched with water
  2. customThe EtOH was removed in vacuo
  3. extractionThe aqueous residue was extracted with CH2Cl2
  4. dry with materialThe organic extracts were dried over Na2SO4
  5. concentrationconcentrated in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-6f44ce3d52c6454cadab13845d9096b1
Quelldatensatz
uspto-grants-2007_07
Patentnummer
US07244738B2

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