2-Amino-6-nitrobenzothiazole → 2,6-Benzothiazolediamine

HRID 130339

Reaktionsgleichung

Reaktionsgleichung von HRID 130339
[NH2:1][C:2]1[S:3][C:4]2[CH:10]=[C:9]([N+:11]([O-])=O)[CH:8]=[CH:7][C:5]=2[N:6]=1.[H][H]>CO.[Pd]>[NH2:1][C:2]1[S:3][C:4]2[CH:10]=[C:9]([NH2:11])[CH:8]=[CH:7][C:5]=2[N:6]=1

Komponenten

5

Edukt 2

HCID 227042-Amino-6-nitrobenzothiazoleHCID 178418361HCID 178418361, Verbindung

Produkt 1

HCID 215042,6-BenzothiazolediamineAusbeute 99,3 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 887MethanolLösungsmittel2×

Versuchsvorschrift

2-Amino-6-nitrobenzothiazole (500 mg, 2.56 mmol) was dissolved in methanol (20 mL) and 10% palladium on carbon (50 mg) was added as a slurry in methanol (1 mL). The atmosphere was replaced with hydrogen and the suspension was stirred overnight. The catalyst was removed by suction filtration and the solvent evaporated to afford 2,6-diaminobenzothiazole (420 mg, 99%) as a pale yellow solid.

Aufarbeitung

  1. customThe catalyst was removed by suction filtration
  2. customthe solvent evaporated

Quellen und Nachweise

ORD-Eintrag
ord-2bb820c6c6b84c03b05572fcc80c66e2
Quelldatensatz
uspto-grants-2008_06
Patentnummer
US07381734B2

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