Reaktionsgleichung
[F:1][C:2]1[CH:9]=[C:8]([F:10])[CH:7]=[CH:6][C:3]=1[CH:4]=O.[C:11]([O:14]C(=O)C)(=[O:13])[CH3:12]>>[F:1][C:2]1[CH:9]=[C:8]([F:10])[CH:7]=[CH:6][C:3]=1[CH:4]=[CH:12][C:11]([OH:14])=[O:13]Komponenten
3
Versuchsvorschrift
A disadvantage here is the high reaction temperature needed, the unsatisfactory yield and the difficult accessibility of the compounds of the formula (I). Monatshefte der Chemie 90, 680 (1959) describes the reaction of 2,4-difluorobenzaldehyde with acetic anhydride at 180° C., 2,4-difluoro-cinnamic acid being obtained in a 77% yield.
Aufarbeitung
- customthe unsatisfactory yield
Quellen und Nachweise
- ORD-Eintrag
- ord-713f7e8e136d41799a23ae377085f383
- Quelldatensatz
- uspto-grants-2008_06
- Patentnummer
- US07381832B2
Verknüpfte Notizen
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