N-(2-Methoxy-5-nitrobenzyl)acetamide → HCID 58629454, Verbindung

HRID 131667Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 131667
[CH3:1][O:2][C:3]1[CH:13]=[CH:12][C:11]([N+:14]([O-])=O)=[CH:10][C:4]=1[CH2:5][NH:6][C:7](=[O:9])[CH3:8].[H][H]>[Pd].C(O)C>[C:7]([NH:6][CH2:5][C:4]1[CH:10]=[C:11]([CH:12]=[CH:13][C:3]=1[O:2][CH3:1])[NH2:14])(=[O:9])[CH3:8]

Komponenten

5

Edukt 2

HCID 20650534N-(2-Methoxy-5-nitrobenzyl)acetamideHCID 178418361HCID 178418361, Verbindung

Produkt 1

HCID 58629454HCID 58629454, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 702EthanolLösungsmittel

Versuchsvorschrift

N-(2-Methoxy-5-nitrobenzyl)acetamide (5 g), with palladium on carbon (1 g) in ethanol (50 ml) was hydrogenated at room temperature under 104 tms. of hydrogen. The reaction was filtered through celite and the ethanol distilled from the filtrate. The residue was recrystallised from benzene to give 3-(acetylaminomethyl)-4-methoxyaniline as pale brown needles. MP; 123-125° C.

Aufarbeitung

  1. customwas hydrogenated at room temperature under 104 tms
  2. filtrationThe reaction was filtered through celite
  3. distillationthe ethanol distilled from the filtrate
  4. customThe residue was recrystallised from benzene

Quellen und Nachweise

ORD-Eintrag
ord-2ef501d97cf64e05a715175de250eed0
Quelldatensatz
uspto-grants-2008_06
Patentnummer
US07384963B2

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