Ethyl Acetoacetate → 5-Methyl-1-(1-methyl-piperidin-4-yl)-1H-pyrazole-4-carbaldehyde

HRID 1350757

Reaktionsgleichung

C(OCC)(=O)CC(C)=O.[CH3:10][N:11]1[CH2:16][CH2:15][CH:14]([NH:17][NH2:18])[CH2:13][CH2:12]1.[CH:19]1([C:22]2N(C(C)C)N=[CH:24][C:23]=2[CH:30]=[O:31])CC1>>[CH3:19][C:22]1[N:17]([CH:14]2[CH2:15][CH2:16][N:11]([CH3:10])[CH2:12][CH2:13]2)[N:18]=[CH:24][C:23]=1[CH:30]=[O:31]

Komponenten

Edukt 3

HCID 8868Ethyl Acetoacetate

HCID 109205354-Hydrazinyl-1-methylpiperidine

HCID 196201355-cyclopropyl-1-(propan-2-yl)-1H-pyrazole-4-carbaldehyde

Produkt 1

HCID 210973515-Methyl-1-(1-methyl-piperidin-4-yl)-1H-pyrazole-4-carbaldehyde

Versuchsvorschrift

5-Methyl-1-(1-methyl-piperidin-4-yl)- 1 H-pyrazole-4-carbaldehyde was prepared from ethyl acetoacetate and (1-methyl-piperidin-4-yl)-hydrazine in the same manner as 5-cyclopropyl-1-isopropyl-1H-pyrazole-4-carbaldehyde (Example 49).

Quellen und Nachweise

ORD-Eintrag: ord-393ace2ea58f4e7aa85f707026a18967
Quelldatensatz: uspto-grants-2007_05
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US07214802B2

Verknüpfte Notizen

Wird geladen…