3-Iodophthalic acid → 3-Iodophthalic anhydride
Reaktionsgleichung
[I:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:4]([C:5]([OH:7])=O)[C:3]=1[C:11]([OH:13])=[O:12]>C(OC(=O)C)(=O)C>[I:1][C:2]1[C:3]2[C:11](=[O:12])[O:13][C:5](=[O:7])[C:4]=2[CH:8]=[CH:9][CH:10]=1Komponenten
3
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
A solution of 3-iodophthalic acid (0.9 g, 3.08 mmol) in acetic anhydride (5 mL) was heated to reflux under nitrogen overnight. After cooling, the solvent was removed in vacuo and the residue purified by trituration with ethanol to give 4-iodo-2-benzofuran-1,3-dione (0.55 g, 65%).
Aufarbeitung
- temperatureto reflux under nitrogen overnight
- temperatureAfter cooling
- customthe solvent was removed in vacuo
- customthe residue purified by trituration with ethanol
Quellen und Nachweise
- ORD-Eintrag
- ord-4318fe1b7da8414a98ba2ac85f02026d
- Quelldatensatz
- uspto-grants-2007_05
- Patentnummer
- US07217740B2
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