3-Iodophthalic acid → 3-Iodophthalic anhydride

HRID 1351699

Reaktionsgleichung

Reaktionsgleichung von HRID 1351699
[I:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:4]([C:5]([OH:7])=O)[C:3]=1[C:11]([OH:13])=[O:12]>C(OC(=O)C)(=O)C>[I:1][C:2]1[C:3]2[C:11](=[O:12])[O:13][C:5](=[O:7])[C:4]=2[CH:8]=[CH:9][CH:10]=1

Komponenten

3

Edukt 1

HCID 2382313-Iodophthalic acid

Produkt 1

HCID 2820713-Iodophthalic anhydrideAusbeute 65,2 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 7918Acetic AnhydrideLösungsmittel

Versuchsvorschrift

A solution of 3-iodophthalic acid (0.9 g, 3.08 mmol) in acetic anhydride (5 mL) was heated to reflux under nitrogen overnight. After cooling, the solvent was removed in vacuo and the residue purified by trituration with ethanol to give 4-iodo-2-benzofuran-1,3-dione (0.55 g, 65%).

Aufarbeitung

  1. temperatureto reflux under nitrogen overnight
  2. temperatureAfter cooling
  3. customthe solvent was removed in vacuo
  4. customthe residue purified by trituration with ethanol

Quellen und Nachweise

ORD-Eintrag
ord-4318fe1b7da8414a98ba2ac85f02026d
Quelldatensatz
uspto-grants-2007_05
Patentnummer
US07217740B2

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