HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1352794Erstellt: 27. Oktober 2026
Thionyl Chloride → 4-(3-Chloro-4-methoxybenzylamino)-5-chloroformyl-6-chloro-2-methylthiopyrimidine
https://huagongshe.com/reaction/1352794
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
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| Edukt | Thionyl Chloride | HCID 24386 | — |
| Edukt | 4-(3-Chloro-4-methoxybenzylamino)-5-carboxy-6-chloro-2-methylthiopyrimidine | HCID 17848268 | — |
| Produkt | 4-(3-Chloro-4-methoxybenzylamino)-5-chloroformyl-6-chloro-2-methylthiopyrimidine | HCID 17848283 | — |
Reaktionsschritte
A mixture of 4-(3-chloro-4-methoxybenzylamino)-5-carboxy-6-chloro-2-methylthiopyrimidine 10.50 g and thionyl chloride 25 ml is stirred for 20 minutes at 75° C. After reaction thionyl chloride is distilled off and the solvent is removed by azeotrope with methylene chloride to give 4-(3-chloro-4-methoxybenzylamino)-5-chloroformyl-6-chloro-2-methylthiopyrimidine.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patentnummer | US07220736B2 |
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| Quelldatensatz | uspto-grants-2007_05 |
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| ORD ID | ord-6a58b8bf060848999592de0358b5314b |
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| Quellennotiz | uspto-grants-2007_05 |
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