Hydrogen Peroxide → 1-Amino-1H-pyrrole-2-carboxamide
Reaktionsgleichung
[NH2:1][N:2]1[CH:6]=[CH:5][CH:4]=[C:3]1[C:7]#[N:8].[OH-:9].[K+].OO>O>[NH2:1][N:2]1[CH:6]=[CH:5][CH:4]=[C:3]1[C:7]([NH2:8])=[O:9]Komponenten
5
Edukt 3
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
1-Amino-1H-pyrrole-2-carbonitrile (2.52 g, 23.5 mmole) was suspended in 75 ml water, treated with potassium hydroxide (32 g, 0.57 mole), 30% hydrogen peroxide (2 ml) and stirred overnight at room temperature. Cooled reaction mixture to 0° C. for 30 min and isolated product by filtration, washed with cold water and dried under vacuum to give 2.55 g product (yield: 87%)
Aufarbeitung
- temperatureCooled
- customreaction mixture to 0° C. for 30 min
- customisolated product
- filtrationby filtration
- washwashed with cold water
- customdried under vacuum
Quellen und Nachweise
- ORD-Eintrag
- ord-c140a53b42da4d6088b4b1c4a03d58af
- Quelldatensatz
- uspto-grants-2007_05
- Patentnummer
- US07223766B2
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