Acetic Anhydride → (4-Chloro-6-methylpyridin-2-yl)methyl acetate

HRID 1357030Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1357030
[Cl:1][C:2]1[CH:7]=[C:6]([CH3:8])[N+:5]([O-])=[C:4]([CH3:10])[CH:3]=1.[C:11]([O:14]C(=O)C)(=[O:13])[CH3:12]>>[Cl:1][C:2]1[CH:7]=[C:6]([CH3:8])[N:5]=[C:4]([CH2:10][O:14][C:11](=[O:13])[CH3:12])[CH:3]=1

Komponenten

3

Edukt 2

HCID 7918Acetic AnhydrideHCID 5878434-Chloro-2,6-dimethylpyridine 1-oxide

Produkt 1

HCID 18505252(4-Chloro-6-methylpyridin-2-yl)methyl acetate

Versuchsvorschrift

4.0 g (25.4 mmol) of 4-chloro-2,6-dimethylpyridine-1-oxide was dissolved in 12 ml of acetic anhydride. The resultant solution was gradually heated to raise the temperature to the reflux temperature, and the solution was then stirred overnight at the same temperature. The reacted solution was then condensed under reduced pressure to obtain a crude product of acetic 4-chloro-6-methyl-2-pyridinylmethyl ester.

Aufarbeitung

  1. temperatureto raise the temperature to the reflux temperature
  2. customcondensed under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-b874bf9cc70649c696331d3670e0b7f4
Quelldatensatz
uspto-grants-2003_07
Patentnummer
US06589967B1

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